Risks of Blood Transfusion-United States

Infectious Disease   Risk per unit 
 Human Immunodeficiency Virus   1 in 2.3 million 
 Hepatitis C Virus  1 in 1.8 million
 Hepatitis B Virus  1 in 200,000
 Human T-Lymphotropic Virus (HTLV)  1 in 3 million
 Bacterial Sepsis from RBC  1 in 500,000
 Bacterial Sepsis from platelets  1 in 75,000
 West Nile Virus  1 in 7 million
 Babesiosis  Under investigation (Disease prevalence is high in Minnesota) 
 Other infections (syphilis, malaria, Chagas, etc.)  Rare

 Non-infectious Complication   Risk Per Unit 
 Allergic (minor)  1 in 100
 Febrile, Non-hemolytic Reaction   1 in 100
 TACO  1 in 100
 Delayed Hemolysis  1 in 2,500
 TRALI  1 in 5,000
 Acute Hemolysis  1 in 33,000
 Anaphylaxis  Rare 
 Transfusion-Associated GVHD  Extremely Rare