Asthma causes swelling and narrowing of the airways in your lungs. No one is exactly sure what causes asthma. It is believed to be a combination of inherited and environmental factors.
Inside the lungs there are branching airways made of stretchy tissue. Each airway is wrapped with bands of muscle. The airways are more narrow as they go deeper into the lungs. The smallest airways end in clusters of tiny balloon-like air sacs (alveoli). These clusters are surrounded by blood vessels. When you inhale (breathe in), air enters the lungs. It travels down through the airways until it reaches the air sacs. When you exhale (breathe out), air travels up through the airways and out of the lungs. The airways produce mucus that traps particles you breathe in. Normally, the mucus is then swept out of the lungs, by tiny hairs (cilia) that line the airways, to be swallowed or coughed up.
The air you inhale contains oxygen. When oxygen reaches the air sacs, it passes into the blood vessels surrounding the sacs. Your blood then delivers oxygen to all of your cells. Carbon dioxide is removed from the body in a similar way, as you exhale.
People with asthma have very sensitive airways. This means the airways react to certain things called triggers (such as pollen, dust, or smoke) and become swollen and narrowed. Inflammation makes the airways swollen and narrowed. This is a chronic (long-lasting or recurring) problem. The airways may not always be narrowed enough to notice breathing problems.
Symptoms of chronic inflammation:
Shortness of breath
Wheezing (a whistling noise, especially when breathing out)
Low energy or feeling tired
Over time, chronic mild inflammation can lead to permanent scarring of airways and loss of lung function.
When sensitive airways are irritated by a trigger, the muscles around the airways tighten. The lining of the airways swells. Thick, sticky mucus increases and clogs the airways. All of this makes you work harder to keep breathing.
Symptoms of moderate flare-ups:
Coughing, especially at night
Getting tired or out of breath easily
Faster breathing when at rest
Severe flare-ups are life-threatening. They can cause brain damage or death. In a severe flare-up, the muscle tightening, swelling, and mucus production are even worse. Breathing is extremely difficult. Your body can't get enough oxygen and can't remove carbon dioxide. Waste gas is trapped in the alveoli, and gas exchange can’t occur. The body is not getting enough oxygen. Without oxygen, body tissues, especially brain tissue, begin to die. If this goes on for long, it can lead to brain damage or death.
Call 911, or have someone call for you, if you have any of these symptoms and they are not relieved right away by taking your quick-relief medication as prescribed:
Severe difficulty breathing
Being too short of breath to talk or walk
Lips or fingers turning blue
Feeling lightheaded or dizzy, as though you are about to pass out
Peak flow less than 50% of your personal best, if you use peak flow monitoring
Because asthma is a long-term condition, it is important to work with your health care provider to manage it. If you smoke, get help to quit. Know your triggers and figure out how to avoid them. And, it is very important that you take your medications as instructed. That means taking them, even when you feel good.