Hypertension, or high blood pressure, is one of the most preventable causes of heart disease and death in the U.S. And it is incredibly common – about 1 in 3 adults have it. Treatment includes a lifestyle changes, like weight loss and increased activity, but many people also need medication to manage their blood pressure.
Several Fairview Clinics are partnering with a company called Geneticure, a pharmacogentics testing company, to conduct a research study to assess whether a DNA test can help determine which hypertension medications your body would respond to best.
A DNA sample will be collected by swabbing your cheek. Your DNA is only used for this study.
Patients will be put into random groups that either receive medication based on DNA or receive medication based on standard of care for the treatment of hypertension. Participants must commit to eight visits during the course of a year at one of the participating clinic locations.
Patients with uncontrolled hypertension will be asked to discontinue all hypertension medications for four weeks prior to starting newly recommended medications. You’ll also be asked to monitor your blood pressure twice daily using provided home blood pressure cuffs.
For each of the follow-up visits your blood pressure will be taken. You will also be asked to complete surveys before each follow-up visit. Your waist circumference will be measured at your first study visit, last study visit, and possibly at some of your follow-up visits.
Those enrolled will receive $100 for attending all study visits and completing all post-visit surveys. Study visits scheduled after consent are provided at no cost to patients. Visits in which patient is diagnosed with hypertension will be billed to patient’s insurance.
Any tests conducted, medications prescribed, or additional, non-study visits scheduled for hypertension during enrollment will be billed to patient’s insurance (blood test, urine test, etc.)
Visit 1: The start of your study participation
Prescribed Medication: 4 weeks after Visit 1
Visit 2: 6 weeks after Visit 1
Visit 3: 4 weeks after Visit 2
Visit 4: 4 weeks after Visit 3
Visit 5: 6 weeks after Visit 4
Visit 6: 6 weeks after Visit 5
Visit 7: 12 weeks after Visit 6
Visit 8: 16 weeks after Visit 7. Final clinic visit
To be eligible, you need to meet all of the following criteria:
To enroll or learn more about the study please call 651-643-0295 or email email@example.com.
The PGen Study is currently being conducted at the following clinics:Metro
If you believe you have high blood pressure and meet study criteria you can schedule an enrollment visit today by calling 651-643-0295.
Pamela Phelps, Pharm.D., FASHP, is the principle investigator of this study and may be reached at firstname.lastname@example.org. To learn more about Geneticure, please visit geneticure.com. You may look up the PGen Study on the https://clinicaltrials.gov/ database. The Clinical Trials Identifier for the PGen Study is: NCT02988245.