Paul Gigante, MD

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Philosophy of Care:

Providing comprehensive, conservative surgical spine care for chronic neck, back, and limb pain. Also using advanced intraoperative monitoring technology and navigation to provide maximal attention to neurological function in resection of brain tumors, addressing trigeminal neuralgia, and performing deep brain stimulation.

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American Association of Neurological Surgeons Kenneth Shulman Award 2012
Complement inhibition promotes endogenous neurogenesis and sustained anti-inflammatory neuroprotection following reperfused stroke. Ducruet AF, Zacharia BE, Sosunov SA, Gigante PR, et al. PLoS One. 2012;7(6). Evaluation of intraventricular hemorrhage assessment methods for predicting outcome following intracerebral hemorrhage.Hwang BY, Bruce SS, Appelboom G, Piazza MA, Carpenter AM, Gigante PR, Kellner CP, Ducruet AF, Kellner MA, Deb-Sen R, Vaughan KA, Meyers PM, Connolly ES Jr. J Neurosurg. 2012 Jan;116(1):185-92. C1-2 instability from os odontoideum mimicking intramedullary spinal cord tumor. Gigante PR, Feldstein NA, Anderson RC. J Neurosurg Pediatr. 2011 Oct;8(4):363-6. Responsive neurostimulation for the treatment of epilepsy. Gigante PR, R Goodman. Neurosurg Clin N Am. 2011 Oct;22(4):477-80. Efficacy of facial nerve-sparing approach in patients with vestibular schwannomas. Haque R, Wojtasiewicz TJ, Gigante PR, Attiah MA, Huang B, Isaacson SR, Sisti MB. J Neurosurg. 2011 Nov;115(5):917-23. Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage. Gigante PR, et al. Acta Neurochir Suppl. 2011;111:141-4. Alternative surgical approaches in epilepsy. Gigante PR, Goodman RR. Curr Neurol Neurosci Rep. 2011 Aug;11(4):404-8. Advances in neuroprotective strategies: potential therapies for intracerebral hemorrhage. Hwang BY, Appelboom G, Ayer A, Kellner CP, Kotchetkov IS, Gigante PR, Haque R, Kellner M, Connolly ES. Cerebrovasc Dis. 2011;31(3):211-22. Polymorphisms in complement component 3 (C3F) and complement factor H (Y402H) increase the risk of postoperative neurocognitive dysfunction following carotid endarterectomy. Gigante PR, Kotchetkov IS, Kellner CP, Haque R, Ducruet AF, Hwang BY, Solomon RA, Heyer EJ, Connolly ES. J Neurol Neurosurg Psychiatry. 2011 Mar;82(3):247-53. Clinical grading scales in intracerebral hemorrhage. Hwang BY, Appelboom G, Kellner CP, Carpenter AM, Kellner MA, Gigante PR, Sander Connolly E. Neurocrit Care. 2010 Aug;13(1):141-51. Genetic determinants of cerebral vasospasm, delayed cerebral ischemia, and outcome after aneurysmal subarachnoid hemorrhage. Ducruet AF, Gigante PR, Hickman ZL, Zacharia BE, Arias EJ, Grobelny BT, Gorski JW, Mayer SA, Connolly ES Jr. J Cereb Blood Flow Metab. 2010 Apr;30(4):676-88. The Neuroprotective Effect of Genetic Mannose-binding Lectin Deficiency is not Sustained in the Sub-acute Phase of Stroke. Ducruet AF, Sosunov SA, Zacharia BE, Gorski J, Yeh ML, Derosa P, Cohen G, Gigante PR, Connolly ES Jr.Transl Stroke Res. 2011 Dec;2(4):588-599.

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